Article
Gene-environment interactions between CRHR1 variants and physical assault in suicide attempts.
Genes, brain, and behavior - 1 Aug 2011
Ben-Efraim Y J, Wasserman D, Wasserman J, Sokolowski M
Abstract excerpt
Risk factors for suicidal behaviors are partly heritable, including genetic variants that drive diathesis-stress in addition to, or by interaction with, exposure to certain stressful life events (SLEs). Hypothalamic-pituitary-adrenal (HPA) axis regulatory genes are candidates for association with suicide as well as its endophenotypes. Using a family-based design of offspring who attempted suicide (SA) and both...
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