Article
Association, haplotype, and gene-gene interactions of the HPA axis genes with suicidal behaviour in affective disorders.
TheScientificWorldJournal - 1 Jan 2013
Leszczyńska-Rodziewicz Anna, Szczepankiewicz Aleksandra, Pawlak Joanna, Dmitrzak-Weglarz Monika, Hauser Joanna
Abstract excerpt
Family twin and adoption studies have noted the heritability of specific biological factors that influence suicidal behaviour. Exposure to stress is one of the factors that strongly contribute to suicide attempts. The biological response to stress involves the hypothalamic-pituitary-adrenal axis (HPA). Therefore, we found it interesting to study polymorphisms of genes involved in the HPA axis (CRHR1, NR3C1, and...
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