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Article

Investigating the role of early childhood abuse and HPA axis genes in suicide attempters with bipolar disorder.

Psychiatric genetics - 1 Jun 2015

Breen Marie E, Seifuddin Fayaz, Zandi Peter P, Potash James B, Willour Virginia L

Abstract excerpt

OBJECTIVE: Genes and the environment both play a major role in the risk for attempted suicide, and environments harboring stressors, such as early childhood abuse, have been linked to suicidal behavior. Such environments also disrupt the hypothalamic-pituitary-adrenal (HPA) axis pathway, which has been hypothesized to play a role in suicidal behavior. We investigated whether the risk for attempted suicide was...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Receptors, Corticotropin-Releasing Hormone

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Source

Open in PubMed Open full text

Identifiers

PMID: 25714448
DOI: 10.1097/YPG.0000000000000082
PMCID: PMC4412784

Genes

CRHR1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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