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Article

Depression in suicidal males: genetic risk variants in the CRHR1 gene.

Genes, brain, and behavior - 1 Feb 2009

Wasserman D, Wasserman J, Rozanov V, Sokolowski M

Abstract excerpt

Dysregulation in the stress response of the hypothalamic-pituitary-adrenal axis, involving the corticotrophin-releasing hormone and its main receptor (CRHR1), is considered to play a major role in depression and suicidal behavior. To comprehensively map the genetic variation in CRHR1 in relation to suicidality and depression, as a follow-up to our initial report on SNP rs4792887, we analyzed six new single...

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Source

Identifiers

PMID: 19220485
DOI: 10.1111/j.1601-183X.2008.00446.x

Genes

CRHR1

Provenance

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