Polymorphism in CRHR1 gene affects the IL-1β levels in suicidal attempters.

doi:10.1016/j.jpsychires.2016.11.009

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Article

Polymorphism in CRHR1 gene affects the IL-1β levels in suicidal attempters.

Journal of psychiatric research - 1 Mar 2017

Bastos Clarissa R, Gazal Marta, Quevedo Luciana de A, Costa Joice Luisa, Wiener Carolina D, Jansen Karen, de Mola Christian Loret, Oses Jean P, Souza Luciano D M, Portela Luiz Valmor, Pinheiro Ricardo T, da Silva Ricardo A, Lara Diogo R, Ghisleni Gabriele

Abstract excerpt

Approximately one million people commit suicide every year, being suicide attempts and ideation even more common. Changes in stress response and activation of the immune system have been associated with suicide risk. Here we investigated the interaction between immune system and HPA axis alterations in the suicide risk, looking for the influence of rs110402 CRHR1 SNP in the IL-1β levels according to suicide...

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Identifiers

PMID: 27894002
DOI: 10.1016/j.jpsychires.2016.11.009

Genes

CRHR1

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