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Article

Negative life events and corticotropin-releasing-hormone receptor1 gene in recurrent major depressive disorder.

Scientific reports - 1 Jan 2013

Liu Zhongchun, Liu Wanhong, Yao Lihua, Yang Can, Xiao Ling, Wan Qirong, Gao Kai, Wang Huiling, Zhu Fan, Wang Gaohua, Xiao Zheman

Abstract excerpt

Major depressive disorder (MDD) is a long-term, recurrent condition that often takes a chronic course. It seems imperative that research should be focused on gaining a better understanding of what predicts recurrent MDD. As a major mediator of the stress response, corticotropin-releasing-hormone receptor 1 (CRHR1) has been demonstrated to be an important contributor to the pathogenesis of MDD. In this study, we...

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Source

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Identifiers

PMID: 23529111
DOI: 10.1038/srep01548
PMCID: PMC3607833

Genes

CRHR1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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