Article
The role of rs242941, rs1876828, rs242939 and rs110402 polymorphisms of CRHR1 gene and the depression: systematic review and meta-analysis.
Genes & genomics - 1 Nov 2021
Hernández-Díaz Yazmín, González-Castro Thelma Beatriz, Juárez-Rojop Isela Esther, Tovilla-Zárate Carlos Alfonso, López-Narváez María Lilia, Genis-Mendoza Alma Delia, Fresan Ana, Nicolini Humberto
Abstract excerpt
BACKGROUND: Several studies have evaluated the possible association between polymorphisms or variants in Corticotropin-releasing hormone 1 receptor gene (CRHR1) with depression; however, results remain contradictory and heterogeneous. OBJECTIVE: To our knowledge, we conducted the first comprehensive systematic review and meta-analysis evaluating the association of the CRHR1 gene and the risk of depression....
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