Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Association of the interleukin-2 receptor alpha (IL-2Ralpha)/CD25 gene region with Graves' disease using a multilocus test and tag SNPs.

Clinical endocrinology - 1 Apr 2007

Brand Oliver J, Lowe Christopher E, Heward Joanne M, Franklyn Jayne A, Cooper Jason D, Todd John A, Gough Stephen C L

Abstract excerpt

OBJECTIVE: A small number of immune response genes have been consistently associated with the common autoimmune conditions. Recently, a linkage disequilibrium (LD) mapping approach, using tag single nucleotide polymorphisms (SNPs), identified genetic association between type 1 diabetes (T1D) and the interleukin-2 receptor alpha (IL-2Ralpha)/CD25 gene region on chromosome 10p15. Because certain autoimmune...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Diabetes Mellitus, Type 1
Share to Graves Disease

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Health Surveys

Share to Interleukin-2 Receptor alpha Subunit

Share to Logistic Models

Share to Odds Ratio

Share to Sequence Tagged Sites

Share to United Kingdom

Source

Identifiers

PMID: 17371467
DOI: 10.1111/j.1365-2265.2007.02762.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Association of the interleukin-2 receptor alpha (IL-2Ralpha)/CD25 gene region with Graves' disease using a multilocus test and tag SNPs.PMID 17371467Read ↗

Localization of a type 1 diabetes locus in the IL2RA/CD25 region by use of tag single-nucleotide polymorphisms.Semantic proximity Read ↗

Association of the IL2RA/CD25 gene with juvenile idiopathic arthritis.Semantic proximity Read ↗

A variant of the Il2ra / Cd25 gene predisposing to graves' disease is associated with increased levels of soluble interleukin-2 receptor.Semantic proximity Read ↗

Tag SNP screening of the PDCD1 gene for association with Graves' disease.Semantic proximity Read ↗

Analysis of Polymorphisms rs7093069-IL-2RA, rs7138803-FAIM2, and rs1748033-PADI4 in the Group of Adolescents With Autoimmune Thyroid Diseases.Semantic proximity Read ↗

Dense mapping of IL2RA shows no association with Graves' disease in Chinese Han population.Semantic proximity Read ↗

Robust evidence for five new Graves' disease risk loci from a staged genome-wide association analysis.Semantic proximity Read ↗

IL2RA/CD25 gene polymorphisms: uneven association with multiple sclerosis (MS) and type 1 diabetes (T1D).Semantic proximity Read ↗

A genome-wide screen in 1119 relative pairs with autoimmune thyroid disease.Semantic proximity Read ↗

Association of the thyroid stimulating hormone receptor gene (TSHR) with Graves' disease.Semantic proximity Read ↗

Predisposition to Graves' disease and Graves' ophthalmopathy by genetic variants of IL2RA.Semantic proximity Read ↗

A new Graves disease-susceptibility locus maps to chromosome 20q11.2. International Consortium for the Genetics of Autoimmune Thyroid Disease.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.