Article
Dense mapping of IL2RA shows no association with Graves' disease in Chinese Han population.
Clinical endocrinology - 1 Aug 2013
Song Zhi-Yi, Liu Wei, Xue Li-Qiong, Pan Chun-Ming, Wang Hai-Ning, Gu Zhao-Hui, Yang Shao-Ying, Cao Huang-Ming, Zuo Chun-Lin, Zhang Xiao-Na, Jiang He, Liu Bing-Li, Bi Ya-Xin, Zhang Xiao-Mei, Zhao Shuang-Xia, Song Huai-Dong
Abstract excerpt
OBJECTIVE: Associations between IL2RA and various autoimmune diseases have been reported in Caucasians. We investigated whether genetic polymorphisms at the IL2RA locus were associated with Graves' disease (GD) in the Chinese Han population. DESIGN: We performed a genome-wide association study (GWAS) in 1 536 GD patients and 1 516 controls. The 1000 Genomes Project data were adopted as references for imputation...
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