Article
Analysis of Polymorphisms rs7093069-IL-2RA, rs7138803-FAIM2, and rs1748033-PADI4 in the Group of Adolescents With Autoimmune Thyroid Diseases.
Frontiers in endocrinology - 1 Jan 2020
Sawicka Beata, Borysewicz-Sańczyk Hanna, Wawrusiewicz-Kurylonek Natalia, Aversa Tommaso, Corica Domenico, Gościk Joanna, Krętowski Adam, Waśniewska Małgorzata, Bossowski Artur
Abstract excerpt
Introduction: The pathogenesis of autoimmune thyroid diseases is complicated and not completely known. Among the causes of thyroid autoimmunity, we distinguish genetic predisposition and environmental factors. Graves' disease and Hashimoto's thyroiditis are associated with a disturbance of immune tolerance of thyroid antigen molecules. The IL2RA gene is located on chromosome 10 and encodes the interleukin 2...
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