Article
A genome-wide screen in 1119 relative pairs with autoimmune thyroid disease.
The Journal of clinical endocrinology and metabolism - 1 Feb 2006
Taylor J C, Gough S C, Hunt P J, Brix T H, Chatterjee K, Connell J M, Franklyn J A, Hegedus L, Robinson B G, Wiersinga W M, Wass J A H, Zabaneh D, Mackay I, Weetman A P
Abstract excerpt
CONTEXT: Autoimmune thyroid diseases (AITD), comprising Graves' disease and autoimmune hypothyroidism, are characterized by loss of immunological self-tolerance to thyroid antigens. These are complex diseases arising from a combination of genetic and environmental factors. An understanding of the genetic susceptibility factors for AITD could help to target treatments more effectively and identify people at risk...
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