Article
Tag SNP screening of the PDCD1 gene for association with Graves' disease.
Clinical endocrinology - 1 Jul 2007
Newby P R, Roberts-Davies E L, Brand O J, Heward J M, Franklyn J A, Gough S C L, Simmonds M J
Abstract excerpt
OBJECTIVE: The Programmed Cell Death 1 gene (PDCD1) on chromosome 2q37.3 encodes PD-1 which is involved in providing a negative signal to activated T cells. Large case-control studies have shown association of PDCD1 with several autoimmune diseases although, to date, no such studies have been per...
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