Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Tag SNP screening of the PDCD1 gene for association with Graves' disease.

Clinical endocrinology - 1 Jul 2007

Newby P R, Roberts-Davies E L, Brand O J, Heward J M, Franklyn J A, Gough S C L, Simmonds M J

Abstract excerpt

OBJECTIVE: The Programmed Cell Death 1 gene (PDCD1) on chromosome 2q37.3 encodes PD-1 which is involved in providing a negative signal to activated T cells. Large case-control studies have shown association of PDCD1 with several autoimmune diseases although, to date, no such studies have been performed for Graves' disease (GD). The objective of our study was to investigate eight tag SNPs representing the majority...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antigens, CD
Share to Apoptosis Regulatory Proteins

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Chi-Square Distribution

Share to Databases, Genetic

Share to Graves Disease

Share to Odds Ratio

Share to Programmed Cell Death 1 Receptor

Source

Identifiers

PMID: 17490403
DOI: 10.1111/j.1365-2265.2007.02848.x

Genes

PDCD1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Tag SNP screening of the PDCD1 gene for association with Graves' disease.PMID 17490403Read ↗

Programmed death ligand 1 (PD-L1) gene variants contribute to autoimmune Addison's disease and Graves' disease susceptibility.Semantic proximity Read ↗

Use of Tag single nucleotide polymorphisms (SNPs) to screen PTPN21: no association with Graves' disease.Semantic proximity Read ↗

Robust evidence for five new Graves' disease risk loci from a staged genome-wide association analysis.Semantic proximity Read ↗

Dissecting the Genetic Susceptibility to Graves’ Disease in a Cohort of Patients of Italian OriginSemantic proximity Read ↗

The genetics of Graves' disease.Semantic proximity Read ↗

Identification of independent risk loci for Graves' disease within the MHC in the Japanese population.Semantic proximity Read ↗

The genetics of Graves' disease.Semantic proximity Read ↗

Evidence for a Graves' disease susceptibility locus at chromosome Xp11 in a United Kingdom population.Semantic proximity Read ↗

Follow-up of potential novel Graves' disease susceptibility loci, identified in the UK WTCCC genome-wide nonsynonymous SNP study.Semantic proximity Read ↗

Genome-wide scan of Graves' disease: evidence for linkage on chromosome 5q31 in Chinese Han pedigrees.Semantic proximity Read ↗

Lack of association of the vitamin D receptor gene with Graves' disease in UK Caucasians.Semantic proximity Read ↗

The replication of the association of the rs6832151 within chromosomal band 4p14 with Graves' disease in a Polish Caucasian population.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.