Article
A new Graves disease-susceptibility locus maps to chromosome 20q11.2. International Consortium for the Genetics of Autoimmune Thyroid Disease.
American journal of human genetics - 1 Dec 1998
Tomer Y, Barbesino G, Greenberg D A, Concepcion E, Davies T F
Abstract excerpt
The autoimmune thyroid diseases (AITDs) include two related disorders, Graves disease (GD) and Hashimoto thyroiditis, in which perturbations of immune regulation result in an immune attack on the thyroid gland. The AITDs are multifactorial and develop in genetically susceptible individuals. Howev...
Topics
- Autoantibodies
- Chromosome Mapping
- Chromosomes, Human, Pair 20
- Europe
- Family Health
- Female
- Genetic Heterogeneity
- Genetic Predisposition to Disease
- Graves Disease
- Humans
- Lod Score
- Male
- Microsatellite Repeats
- Models, Genetic
- North America