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Article

Genetic effects on bone mechanotransduction in congenic mice harboring bone size and strength quantitative trait loci.

Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research - 1 Jul 2007

Robling Alexander G, Warden Stuart J, Shultz Kathryn L, Beamer Wesley G, Turner Charles H

Abstract excerpt

UNLABELLED: The degree to which bone tissue responds to mechanical loading events is partially under genetic control. We assess the contribution of three genetic loci (QTLs linked to bone geometry and strength)--located on mouse Chrs. 1, 8, and 13--to mechanically stimulated bone formation, through in vivo skeletal loading of congenic strains. Bone size was not consistently associated with mechano-responsiveness,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 17371164
DOI: 10.1359/jbmr.070327

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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