Article
Genetic effects for femoral biomechanics, structure, and density in C57BL/6J and C3H/HeJ inbred mouse strains.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research - 1 Oct 2003
Koller Daniel L, Schriefer Jennifer, Sun Qiwei, Shultz Kathryn L, Donahue Leah R, Rosen Clifford J, Foroud Tatiana, Beamer Wesley G, Turner Charles H
Abstract excerpt
UNLABELLED: Genome-wide QTL analysis for bone density, structure, and biomechanical phenotypes was performed in 999 (B6xC3H)F2 mice. Multivariate phenotypes were also derived to test for pleiotropic QTL effects. Highly significant QTLs were detected with pleiotropic effects on many of these phenotypes, and QTLs with unique effects on specific phenotypes were found as well. INTRODUCTION: The inbred C57BL/6J (B6)...
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