Article
Comprehensive skeletal phenotyping and linkage mapping in an intercross of recombinant congenic mouse strains HcB-8 and HcB-23.
Cells, tissues, organs - 1 Jan 2011
Saless Neema, Litscher Suzanne J, Houlihan Meghan J, Han In Kyu, Wilson Derek, Demant Peter, Blank Robert D
Abstract excerpt
Bone biomechanical performance is a complex trait or, more properly, an ensemble of complex traits. Biomechanical performance incorporates flexibility under loading, yield and failure load, and energy to failure; all are important measures of bone function. To date, the vast majority of work has focused on yield and failure load and its surrogate, bone mineral density. We performed a reciprocal intercross of the...
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