Article
Quantitative trait loci analysis of structural and material skeletal phenotypes in C57BL/6J and DBA/2 second-generation and recombinant inbred mice.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research - 1 Jan 2005
Lang Dean H, Sharkey Neil A, Mack Holly A, Vogler George P, Vandenbergh David J, Blizard David A, Stout Joseph T, McClearn Gerald E
Abstract excerpt
UNLABELLED: QTL analyses identified several chromosomal regions influencing skeletal phenotypes of the femur and tibia in BXD F2 and BXD RI populations of mice. QTLs for skeletal traits co-located with each other and with correlated traits such as body weight and length, adipose mass, and serum alkaline phosphatase. INTRODUCTION: Past research has shown substantial genetic influence on bone quality, and the...
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