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Article

Identification of genetic loci that regulate bone adaptive response to mechanical loading in C57BL/6J and C3H/HeJ mice intercross.

Bone - 1 Sept 2006

Kesavan Chandrasekhar, Mohan Subburaman, Srivastava Apurva K, Kapoor Susanna, Wergedal Jon E, Yu Hongrun, Baylink David J

Abstract excerpt

Strain-dependent differences in bone adaptive responses to loading among inbred mouse strains suggest that genetic background contributes significantly to adaptation to exercise. To explore the genetic regulation of response to loading, we performed a genome-wide search for linkage in a cross between two strains, a good responder, C57BL6/J (B6), and a poor responder, C3H/HeJ (C3H). Using a four-point bending...

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PMID: 16713414
DOI: 10.1016/j.bone.2006.03.005

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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