Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genetic dissection of mouse distal chromosome 1 reveals three linked BMD QTLs with sex-dependent regulation of bone phenotypes.

Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research - 1 Aug 2007

Beamer Wesley G, Shultz Kathryn L, Ackert-Bicknell Cheryl L, Horton Lindsay G, Delahunty Krista M, Coombs Harold F, Donahue Leah R, Canalis Ernesto, Rosen Clifford J

Abstract excerpt

UNLABELLED: Genetic analyses with mouse congenic strains for distal Chr1 have identified three closely linked QTLs regulating femoral vBMD, mid-diaphyseal cortical thickness, and trabecular microstructure in a sex-dependent fashion. The homologous relationship between distal mouse Chr 1 and human 1q21-24 offers the possibility of finding common regulatory genes for cortical and trabecular bone. INTRODUCTION: The...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bone Density
Share to Chromosomes, Mammalian

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Dissection

Share to Haplotypes

Share to Quantitative Trait Loci

Share to Sex Characteristics

Source

Identifiers

PMID: 17451375
DOI: 10.1359/jbmr.070419

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genetic dissection of mouse distal chromosome 1 reveals three linked BMD QTLs with sex-dependent regulation of bone phenotypes.PMID 17451375Read ↗

Multiple genetic loci from CAST/EiJ chromosome 1 affect vBMD either positively or negatively in a C57BL/6J background.Semantic proximity Read ↗

Multiple quantitative trait loci for cortical and trabecular bone regulation map to mid-distal mouse chromosome 4 that shares linkage homology to human chromosome 1p36.Semantic proximity Read ↗

Genetic regulation of femoral bone mineral density: complexity of sex effect in chromosome 1 revealed by congenic sublines of mice.Semantic proximity Read ↗

Mapping Quantitative Trait Loci for Vertebral Trabecular Bone Volume Fraction and Microarchitecture in MiceSemantic proximity Read ↗

Congenic strains of mice for verification and genetic decomposition of quantitative trait loci for femoral bone mineral density.Semantic proximity Read ↗

Identification of gender-specific candidate genes that influence bone microarchitecture in chromosome 1.Semantic proximity Read ↗

Genome-wide association study in Collaborative Cross mice reveals a role for <i>Rhbdf2</i> in skeletal homeostasisSemantic proximity Read ↗

Confirmation and fine mapping of chromosomal regions influencing peak bone mass in mice.Semantic proximity Read ↗

Fine mapping reveals sex bias in quantitative trait loci affecting growth, skeletal size and obesity-related traits on mouse chromosomes 2 and 11.Semantic proximity Read ↗

Linkage screen for BMD phenotypes in male and female COP and DA rat strains.Semantic proximity Read ↗

Collaborative cross mice in a genetic association study reveal new candidate genes for bone microarchitecture.Semantic proximity Read ↗

Congenic mice reveal sex-specific genetic regulation of femoral structure and strength.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.