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Article

Evidence for a skeletal mechanosensitivity gene on mouse chromosome 4

18 Dec 2002

Abstract excerpt

Differences in skeletal mechanical adaptation between C3H/HeJ (C3H) and C57BL/6J (B6) mouse strains suggest that these mice can be used to elucidate the genes involved in mechanosensitivity regulation. The C3H and B6 skeletons also differ in bone size, and several quantitative trait loci (QTL) have been mapped for bone size. We hypothesized that genes controlling bone size (external diameter) might exert their...

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PMID: 12490544
DOI: 10.1096/fj.02-0393fje

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