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Article

Mobility and distribution of replication protein A in living cells using fluorescence correlation spectroscopy.

Experimental and molecular pathology - 1 Apr 2007

Braet Christophe, Stephan Holger, Dobbie Ian M, Togashi Denisio M, Ryder Alan G, Földes-Papp Zeno, Lowndes Noel, Nasheuer Heinz Peter

Abstract excerpt

Replication protein A (RPA), the eukaryotic single-stranded DNA (ssDNA) binding protein, is essential for all pathways of DNA metabolism. To study the function of RPA in living cells the second largest RPA subunit and an N-terminal deletion mutant thereof were fused to green fluorescent protein (GFP; GFP-RPA2 and GFP-RPA2deltaN, respectively) in a controlled, molecular biological way. These proteins were...

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Source

Identifiers

PMID: 17303118
DOI: 10.1016/j.yexmp.2006.12.008

Genes

RPA2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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