Fluorescence correlation spectroscopy and its potential for intracellular applications.

doi:10.1385/CBB:34:3:383

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Article

Fluorescence correlation spectroscopy and its potential for intracellular applications.

Cell biochemistry and biophysics - 1 Jan 2001

Schwille P

Abstract excerpt

Fluorescence correlation spectroscopy (FCS) is a time-averaging fluctuation analysis of small molecular ensembles, combining maximum sensitivity with high statistical confidence. Among a multitude of physical parameters that are, in principle, accessible by FCS, it most conveniently allows to determine local concentrations, mobility coefficients, and characteristic rate constants of fast-reversible and...

Topics

Cell Membrane
Green Fluorescent Proteins
Luminescent Proteins
Microscopy, Confocal
Models, Statistical
Mutation
Photons
Spectrometry, Fluorescence
Time Factors

Source

Open in PubMed

Identifiers

PMID: 11898862
DOI: 10.1385/CBB:34:3:383

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

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