Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The transcription cycle of RNA polymerase II in living cells.

The Journal of cell biology - 9 Dec 2002

Kimura Hiroshi, Sugaya Kimihiko, Cook Peter R

Abstract excerpt

RNA polymerase II transcribes most eukaryotic genes. Its catalytic subunit was tagged with green fluorescent protein and expressed in Chinese hamster cells bearing a mutation in the same subunit; it complemented the defect and so was functional. Photobleaching revealed two kinetic fractions of polymerase in living nuclei: approximately 75% moved rapidly, but approximately 25% was transiently immobile (association...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cricetinae
Share to Dactinomycin
Share to Gene Expression Regulation, Enzymologic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Green Fluorescent Proteins

Share to Luminescent Proteins

Share to Nucleic Acid Synthesis Inhibitors

Share to Periodicity

Share to RNA Polymerase II

Source

Open in PubMed Open full text

Identifiers

PMID: 12473686
DOI: 10.1083/jcb.200206019
PMCID: PMC2173384

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The transcription cycle of RNA polymerase II in living cells.PMID 12473686Read ↗

The transcriptional cycle of HIV-1 in real-time and live cells.Semantic proximity Read ↗

Single-molecule live imaging of subunit interactions and exchange within cellular regulatory complexesSemantic proximity Read ↗

Zooming in on single active genes in living mammalian cells.Semantic proximity Read ↗

Regulation of TATA-binding protein dynamics in living yeast cells.Semantic proximity Read ↗

Cell-cycle dependent organization and dynamics of RNA Polymerase I in live human cellsSemantic proximity Read ↗

Release of human TFIIB from actively transcribing complexes is triggered upon synthesis of 7 nt and 9 nt RNAsSemantic proximity Read ↗

RNA polymerase II initiation factors show different dynamic behaviour upon induced transcription in live cellsSemantic proximity Read ↗

Transcription, one allele at a time.Semantic proximity Read ↗

RNA polymerase II transcription complex assembly in nuclear extracts.Semantic proximity Read ↗

Real-time chromatin dynamics at the single gene level during transcription activationSemantic proximity Read ↗

Single-molecule microscopy reveals that TFIIE subunits dynamically interact with preinitiation complexes in a manner controlled by TFIIHSemantic proximity Read ↗

Piggybacking functionalized DNA nanostructures into live cell nucleiSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.