Article
RAD51C (RAD51L2) is involved in maintaining centrosome number in mitosis.
Cytogenetic and genome research - 1 Jan 2007
Renglin Lindh A, Schultz N, Saleh-Gohari N, Helleday T
Abstract excerpt
The RAD51C (RAD51L2) protein is one out of five RAD51 paralogs and forms a complex that includes either XRCC2 or XRCC3. Both of these complexes may have important functions in homologous recombination (HR). Here, we confirm that the frequency of DNA double-strand break (DSB)-induced HR is reduced in the RAD51C deficient cell line CL-V4B, in agreement with a role for RAD51C in HR. We report that mitotic RAD51C...
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