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Involvement of Rad51C in two distinct protein complexes of Rad51 paralogs in human cells

15 Feb 2002

Abstract excerpt

Genetic studies in rodent and chicken mutant cell lines have suggested that Rad51 paralogs (XRCC2, XRCC3, Rad51B/Rad51L1, Rad51C/Rad51L2 and Rad51D/Rad51L3) play important roles in homologous recombinational repair of DNA double-strand breaks and in maintaining chromosome stability. Previous studies using yeast two- and three-hybrid systems have shown interactions among these proteins, but it is not clear whether...

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PMID: 11842113
DOI: 10.1093/nar/30.4.1009

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