Article
RAD51C: a novel cancer susceptibility gene is linked to Fanconi anemia and breast cancer.
Carcinogenesis - 1 Dec 2010
Somyajit Kumar, Subramanya Shreelakshmi, Nagaraju Ganesh
Abstract excerpt
Germline mutations in many of the genes that are involved in homologous recombination (HR)-mediated DNA double-strand break repair (DSBR) are associated with various human genetic disorders and cancer. RAD51 and RAD51 paralogs are important for HR and in the maintenance of genome stability. Despite the identification of five RAD51 paralogs over a decade ago, the molecular mechanism(s) by which RAD51 paralogs...
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