Article
The Rad51 paralog Rad51B promotes homologous recombinational repair.
Molecular and cellular biology - 1 Sept 2000
Takata M, Sasaki M S, Sonoda E, Fukushima T, Morrison C, Albala J S, Swagemakers S M, Kanaar R, Thompson L H, Takeda S
Abstract excerpt
The highly conserved Saccharomyces cerevisiae Rad51 protein plays a central role in both mitotic and meiotic homologous DNA recombination. Seven members of the Rad51 family have been identified in vertebrate cells, including Rad51, Dmc1, and five Rad51-related proteins referred to as Rad51 paralogs, which share 20 to 30% sequence identity with Rad51. In chicken B lymphocyte DT40 cells, we generated a mutant with...
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