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Article

Differentiated human alveolar epithelial cells and reversibility of their phenotype in vitro.

American journal of respiratory cell and molecular biology - 1 Jun 2007

Wang Jieru, Edeen Karen, Manzer Rizwan, Chang Yongsheng, Wang Shuanglin, Chen Xueni, Funk C Joel, Cosgrove Gregory P, Fang Xiaohui, Mason Robert J

Abstract excerpt

Cultures of differentiating fetal human type II cells have been available for many years. However, studies with differentiated adult human type II cells are limited. We used a published method for type II cell isolation and developed primary culture systems for maintenance of differentiated adult human alveolar epithelial cells for in vitro studies. Human type II cells cultured on Matrigel (basolateral access) or...

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Identifiers

PMID: 17255555
DOI: 10.1165/rcmb.2006-0410OC
PMCID: PMC1899340

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