Article
Primary cell culture of human type II pneumonocytes: maintenance of a differentiated phenotype and transfection with recombinant adenoviruses.
American journal of respiratory cell and molecular biology - 1 Dec 1997
Alcorn J L, Smith M E, Smith J F, Margraf L R, Mendelson C R
Abstract excerpt
Studies of the regulation of surfactant lipoprotein metabolism and secretion and surfactant protein gene expression have been hampered by the lack of a cell culture system in which the phenotypic properties of type II cells are maintained. We have developed a primary culture system that facilitates the maintenance of a number of morphologic and biochemical properties of type II pneumonocytes for up to 2 wk. Cells...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.