Article
Extracellular matrix-driven alveolar epithelial cell differentiation in vitro.
Experimental lung research - 1 Jun 2005
Olsen Colin O, Isakson Brant E, Seedorf Gregory J, Lubman Richard L, Boitano Scott
Abstract excerpt
During homeostasis and in response to injury, alveolar type II (AT2) cells serve as progenitor cells to proliferate, migrate, differentiate, and re-establish both alveolar type I (AT1) and AT2 cells into a functional alveolar epithelium. To understand specific changes in cell differentiation, we monitored morphological characteristics and cell-specific protein markers over time for isolated rat AT2 cells cultured...
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