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Article

Spectral monitoring of surfactant clearance during alveolar epithelial type II cell differentiation.

Biophysical journal - 15 Dec 2008

Swain Robin J, Kemp Sarah J, Goldstraw Peter, Tetley Teresa D, Stevens Molly M

Abstract excerpt

In this study, we report on the noninvasive identification of spectral markers of alveolar type II (ATII) cell differentiation in vitro using Raman microspectroscopy. ATII cells are progenitor cells for alveolar type I (ATI) cells in vivo, and spontaneously differentiate toward an ATI-like phenotype in culture. We analyzed undifferentiated and differentiated primary human ATII cells, and correlated Raman spectral...

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Identifiers

PMID: 18820234
DOI: 10.1529/biophysj.108.136168
PMCID: PMC2599825

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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