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Article

Dual effect of APOBEC3G on Hepatitis B virus.

The Journal of general virology - 1 Feb 2007

Noguchi Chiemi, Hiraga Nobuhiko, Mori Nami, Tsuge Masataka, Imamura Michio, Takahashi Shoichi, Fujimoto Yoshifumi, Ochi Hidenori, Abe Hiromi, Maekawa Toshiro, Yatsuji Hiromi, Shirakawa Kotaro, Takaori-Kondo Akifumi, Chayama Kazuaki

Abstract excerpt

G to A hypermutation of Hepatitis B virus (HBV) and retroviruses appears as a result of deamination activities of host APOBEC proteins and is thought to play a role in innate antiviral immunity. Alpha and gamma interferons (IFN-alpha and -gamma) have been reported to upregulate the transcription of APOBEC3G, which is known to reduce the replication of HBV. We investigated the number of hypermutated genomes under...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 17251560
DOI: 10.1099/vir.0.82319-0

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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