Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Extensive editing of both hepatitis B virus DNA strands by APOBEC3 cytidine deaminases <i>in vitro</i> and <i>in vivo</i>

26 May 2005

Abstract excerpt

Because the replication of hepatitis B virus (HBV) proceeds via an obligatory reverse transcription step in the viral capsid, cDNA is potentially vulnerable to editing by cytidine deaminases of the APOBEC3 family. To date only two edited HBV genomes, referred to as G --> A hypermutants, have been described in vivo. Recent work suggested that HBV replication was indeed restricted by APOBEC3G but by a mechanism...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bacteriophages and microbial interactions
Share to Hepatitis B Virus Studies
Share to HIV Research and Treatment

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 15919829
DOI: 10.1073/pnas.0408223102

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Extensive editing of both hepatitis B virus DNA strands by APOBEC3 cytidine deaminases <i>in vitro</i> and <i>in vivo</i>PMID 15919829Read ↗

The inhibition of hepatitis B virus by <scp>APOBEC</scp> cytidine deaminasesSemantic proximity Read ↗

Deamination-Independent Inhibition of Hepatitis B Virus Reverse Transcription by APOBEC3GSemantic proximity Read ↗

Genetic Editing of Herpes Simplex Virus 1 and Epstein-Barr Herpesvirus Genomes by Human APOBEC3 Cytidine Deaminases in Culture and <i>In Vivo</i>Semantic proximity Read ↗

Hypermutation of hepatitis B virus genomes by APOBEC3G, APOBEC3C and APOBEC3HSemantic proximity Read ↗

APOBEC3-induced mutation of the hepatitis virus B DNA genome occurs during its viral RNA reverse transcription into (-)-DNA.Semantic proximity Read ↗

Hepatitis B virus DNA is subject to extensive editing by the human deaminase APOBEC3C.Semantic proximity Read ↗

Genetic Editing of HBV DNA by Monodomain Human APOBEC3 Cytidine Deaminases and the Recombinant Nature of APOBEC3GSemantic proximity Read ↗

Roles of APOBEC3 in hepatitis B virus (HBV) infection and hepatocarcinogenesis.Semantic proximity Read ↗

A3G-induced mutations show a low prevalence and exhibit plus-strand regional distribution in hepatitis B virus DNA from patients with non-hepatocellular carcinoma (HCC) and HCC.Semantic proximity Read ↗

Extensive editing of a small fraction of human T-cell leukemia virus type 1 genomes by four APOBEC3 cytidine deaminases.Semantic proximity Read ↗

G to A hypermutation of hepatitis B virus.Semantic proximity Read ↗

APOBEC3G-Mediated G-to-A Hypermutation of the HIV-1 Genome: The Missing Link in Antiviral Molecular MechanismsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.