Article
Full genome ultra-deep pyrosequencing associates G-to-A hypermutation of the hepatitis B virus genome with the natural progression of hepatitis B.
Journal of viral hepatitis - 1 Dec 2013
Beggel B, Münk C, Däumer M, Hauck K, Häussinger D, Lengauer T, Erhardt A
Abstract excerpt
Human APOBEC3 (A3) cytosine deaminases are antiviral restriction factors capable of editing the genome the hepatitis B virus (HBV). Despite the importance of the human A3 protein family for the innate immune response little is known about the clinical relevance for hepatitis B. The aim of this st...
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