Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

G to A hypermutation of hepatitis B virus.

Hepatology (Baltimore, Md.) - 1 Mar 2005

Noguchi Chiemi, Ishino Hiromi, Tsuge Masataka, Fujimoto Yoshifumi, Imamura Michio, Takahashi Shoichi, Chayama Kazuaki

Abstract excerpt

G to A hypermutation of the human immunodeficiency virus type 1 (HIV-1) is induced by a deaminase APOBEC3G and is related to host antiviral defense. APOBEC3G has also been found to reduce the replication of HIV-1 by an unknown mechanism. This enzyme also reduces the production of hepatitis B virus, although the mechanism for this action has not been clearly elucidated. The hypermutated hepatitis B virus (HBV) is...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to APOBEC-3G Deaminase
Share to Cytidine Deaminase
Share to Genome, Viral

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Hepatitis B virus

Share to Hepatitis C

Share to Proteins

Share to Repressor Proteins

Share to Virus Replication

Source

Identifiers

PMID: 15726649
DOI: 10.1002/hep.20580

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

G to A hypermutation of hepatitis B virus.PMID 15726649Read ↗

The Disassociation of A3G-Related HIV-1 cDNA G-to-A Hypermutation to Viral Infectivity.Semantic proximity Read ↗

Naturally Occurring Hepatitis B Virus Genomes Bearing the Hallmarks of Retroviral G → A HypermutationSemantic proximity Read ↗

APOBEC3G-Mediated G-to-A Hypermutation of the HIV-1 Genome: The Missing Link in Antiviral Molecular MechanismsSemantic proximity Read ↗

Full genome ultra-deep pyrosequencing associates G-to-A hypermutation of the hepatitis B virus genome with the natural progression of hepatitis B.Semantic proximity Read ↗

APOBEC3G induces a hypermutation gradient: purifying selection at multiple steps during HIV-1 replication results in levels of G-to-A mutations that are high in DNA, intermediate in cellular viral RNA, and low in virion RNA.Semantic proximity Read ↗

[Analysis of G to A hypermutation of HBV in chronic hepatitis B patients].Semantic proximity Read ↗

Extensive editing of both hepatitis B virus DNA strands by APOBEC3 cytidine deaminases <i>in vitro</i> and <i>in vivo</i>Semantic proximity Read ↗

Dual effect of APOBEC3G on Hepatitis B virus.Semantic proximity Read ↗

G-to-A hypermutation in hepatitis B virus (HBV) and clinical course of patients with chronic HBV infection.Semantic proximity Read ↗

Detecting hypermutations in viral sequences with an emphasis on G → A hypermutationSemantic proximity Read ↗

The inhibition of hepatitis B virus by <scp>APOBEC</scp> cytidine deaminasesSemantic proximity Read ↗

APOBEC3-induced mutation of the hepatitis virus B DNA genome occurs during its viral RNA reverse transcription into (-)-DNA.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.