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Article

Deamination-Independent Inhibition of Hepatitis B Virus Reverse Transcription by APOBEC3G

22 Feb 2007

Abstract excerpt

The APOBEC3 family of mammalian cytidine deaminases, including APOBEC3G (A3G), has been shown to function as innate antiviral factors against retroviruses and can also suppress the replication of the hepatitis B virus (HBV). The mechanism by which A3G inhibits HBV replication remains to be elucidated. In this study, we show that the inhibitory effect of APOBEC3 proteins on HBV replication was mainly at the DNA...

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Identifiers

PMID: 17314171
DOI: 10.1128/jvi.02510-06

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Source receipt: pubmed, retrieved 7 Sept 2026.

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