Genome-wide single nucleotide polymorphism analysis of lung cancer risk detects the KLF6 gene.

doi:10.1016/j.canlet.2006.11.029

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Article

Genome-wide single nucleotide polymorphism analysis of lung cancer risk detects the KLF6 gene.

Cancer letters - 28 Jun 2007

Spinola Monica, Leoni Vera P, Galvan Antonella, Korsching Eberhard, Conti Barbara, Pastorino Ugo, Ravagnani Fernando, Columbano Amedeo, Skaug Vidar, Haugen Aage, Dragani Tommaso A

Abstract excerpt

A genome-wide association analysis using the Affymetrix 100K SNP array was carried out in a case-control study of lung cancer. Allele frequencies were estimated initially in DNA pools. Significant differences in allele frequency detected in the SNP array analysis were first tested in the same DNA pools by pyrosequencing and then by individual genotyping. DNA pooling analysis identified rs10508266 SNP, located...

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Identifiers

PMID: 17223258
DOI: 10.1016/j.canlet.2006.11.029

Genes

KLF6

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