Article
Variants in the 5'-upstream region of GPC5 confer risk of lung cancer in never smokers.
Cancer epidemiology - 1 Feb 2014
Liu Li, Zhong Rong, Zou Li, Fu Jinjian, Zhu Beibei, Chen Wei, Ye Xiaohua, Gao Yanhui, Yang Yi, Christiani David C, Chen Sidong, Miao Xiaoping
Abstract excerpt
BACKGROUND: A recent genome-wide study (GWAS) has identified GPC5 as a promising susceptibility gene for Lung cancer in never smokers (LCINS). However, the most significant single nucleotide polymorphism (SNP) in this GWAS, rs2352028, has yielded controversial results. The aim of this study was to clarify the relationship between rs2352028 and LCINS. Considering that rs2352028 might be largely marker-SNP...
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