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Article

Potentially Functional Polymorphisms in POU5F1 Gene Are Associated with the Risk of Lung Cancer in Han Chinese.

BioMed research international - 1 Jan 2015

Niu Rui, Wang Yuzhuo, Zhu Meng, Wen Yifan, Sun Jie, Shen Wei, Cheng Yang, Zhang Jiahui, Jin Guangfu, Ma Hongxia, Hu Zhibin, Shen Hongbing, Dai Juncheng

Abstract excerpt

POU5F1 is a key regulator of self-renewal and differentiation in embryonic stem cells and may be associated with initiation, promotion, and progression in cancer. We hypothesized that functional polymorphisms in POU5F1 may play an important role in modifying the lung cancer risk. To test this hypothesis, we conducted a case-control study to explore the association between 17 potentially functional SNPs in POU5F1...

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Identifiers

PMID: 26824036
DOI: 10.1155/2015/851320
PMCID: PMC4707383

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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