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Article

Genome-wide association study in discordant sibships identifies multiple inherited susceptibility alleles linked to lung cancer.

Carcinogenesis - 1 Mar 2010

Galvan Antonella, Falvella Felicia S, Frullanti Elisa, Spinola Monica, Incarbone Matteo, Nosotti Mario, Santambrogio Luigi, Conti Barbara, Pastorino Ugo, Gonzalez-Neira Anna, Dragani Tommaso A

Abstract excerpt

We analyzed a series of young (median age = 52 years) non-smoker lung cancer patients and their unaffected siblings as controls, using a genome-wide 620 901 single-nucleotide polymorphism (SNP) array analysis and a case-control DNA pooling approach. We identified 82 putatively associated SNPs that were retested by individual genotyping followed by use of the sib transmission disequilibrium test, pointing to 36...

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PMID: 20022890
DOI: 10.1093/carcin/bgp315

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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