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Article

Systematical analyses of variants in CTCF-binding sites identified a novel lung cancer susceptibility locus among Chinese population.

Scientific reports - 16 Jan 2015

Dai Juncheng, Zhu Meng, Wang Cheng, Shen Wei, Zhou Wen, Sun Jie, Liu Jia, Jin Guangfu, Ma Hongxia, Hu Zhibin, Lin Dongxin, Shen Hongbing

Abstract excerpt

Genome-wide association studies identified genetic susceptibility variants mostly lie outside of protein-coding regions. It suggested variants located at transcriptional regulatory region should play an important role in cancer carcinogenesis including lung cancer. In the present study, we systematically investigated the associations between the variants in the binding sites of an extensive transcription factor...

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Identifiers

PMID: 25592173
DOI: 10.1038/srep07833
PMCID: PMC4296290

Genes

CTCF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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