Article
A susceptibility locus on chromosome 6q greatly increases lung cancer risk among light and never smokers.
Cancer research - 15 Mar 2010
Amos Christopher I, Pinney Susan M, Li Yafang, Kupert Elena, Lee Juwon, de Andrade Mariza A, Yang Ping, Schwartz Ann G, Fain Pam R, Gazdar Adi, Minna John, Wiest Jonathan S, Zeng Dong, Rothschild Henry, Mandal Diptasri, You Ming, Coons Teresa, Gaba Colette, Bailey-Wilson Joan E, Anderson Marshall W
Abstract excerpt
Cigarette smoking is the major cause for lung cancer, but genetic factors also affect susceptibility. We studied families that included multiple relatives affected by lung cancer. Results from linkage analysis showed strong evidence that a region of chromosome 6q affects lung cancer risk. To char...
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