Article
MSH6 G39E polymorphism and CpG island methylator phenotype in colon cancer.
Molecular carcinogenesis - 1 Nov 2009
Curtin Karen, Samowitz Wade S, Wolff Roger K, Caan Bette J, Ulrich Cornelia M, Potter John D, Slattery Martha L
Abstract excerpt
The MSH6 G39E germline polymorphism is not associated with an increased risk of either microsatellite stable or unstable sporadic colorectal cancer. Other than microsatellite instability, however, most genetic and epigenetic changes of tumors associated with this common variant have not been studied. The objective of our investigation was to evaluate associations between the MSH6 G39E (116G>A) polymorphism and...
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