Article
Drosophila ATR in double-strand break repair.
Genetics - 1 Mar 2007
LaRocque Jeannine R, Jaklevic Burnley, Su Tin Tin, Sekelsky Jeff
Abstract excerpt
The ability of a cell to sense and respond to DNA damage is essential for genome stability. An important aspect of the response is arrest of the cell cycle, presumably to allow time for repair. Ataxia telangiectasia mutated (ATM) and ATR are essential for such cell-cycle control, but some observations suggest that they also play a direct role in DNA repair. The Drosophila ortholog of ATR, MEI-41, mediates the DNA...
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