Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Epigenetic telomere protection by Drosophila DNA damage response pathways.

PLoS genetics - 1 May 2006

Oikemus Sarah R, Queiroz-Machado Joana, Lai KuanJu, McGinnis Nadine, Sunkel Claudio, Brodsky Michael H

Abstract excerpt

Analysis of terminal deletion chromosomes indicates that a sequence-independent mechanism regulates protection of Drosophila telomeres. Mutations in Drosophila DNA damage response genes such as atm/tefu, mre11, or rad50 disrupt telomere protection and localization of the telomere-associated proteins HP1 and HOAP, suggesting that recognition of chromosome ends contributes to telomere protection. However, the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cell Cycle
Share to Crosses, Genetic
Share to DNA Damage

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to DNA Repair

Share to Drosophila Proteins

Share to Epigenesis, Genetic

Share to Mitosis

Share to Telomere

Source

Open in PubMed Open full text

Identifiers

PMID: 16710445
DOI: 10.1371/journal.pgen.0020071
PMCID: PMC1463044

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Epigenetic telomere protection by Drosophila DNA damage response pathways.PMID 16710445Read ↗

Drosophila atm/telomere fusion is required for telomeric localization of HP1 and telomere position effect.Semantic proximity Read ↗

<i>Drosophila</i> ATM and ATR checkpoint kinases control partially redundant pathways for telomere maintenanceSemantic proximity Read ↗

Multiple pathways suppress telomere addition to DNA breaks in the Drosophila germline.Semantic proximity Read ↗

The terminal telomeric DNA sequence determines the mechanism of dysfunctional telomere fusion.Semantic proximity Read ↗

Organization and Evolution of Drosophila Terminin: Similarities and Differences between Drosophila and Human TelomeresSemantic proximity Read ↗

The Drosophila Mre11/Rad50 complex is required to prevent both telomeric fusion and chromosome breakage.Semantic proximity Read ↗

ATM is required for telomere maintenance and chromosome stability during Drosophila development.Semantic proximity Read ↗

The Drosophila modigliani (moi) gene encodes a HOAP-interacting protein required for telomere protection.Semantic proximity Read ↗

A product of the bicistronic Drosophila melanogaster gene CG31241, which also encodes a trimethylguanosine synthase, plays a role in telomere protection.Semantic proximity Read ↗

The Drosophila Nbs protein functions in multiple pathways for the maintenance of genome stability.Semantic proximity Read ↗

Telomere shortening triggers a feedback loop to enhance end protection.Semantic proximity Read ↗

HipHop interacts with HOAP and HP1 to protect Drosophila telomeres in a sequence-independent manner.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.