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Article

Loss of Drosophila Mei-41/ATR Alters Meiotic Crossover Patterning.

Genetics - 1 Feb 2018

Brady Morgan M, McMahan Susan, Sekelsky Jeff

Abstract excerpt

Meiotic crossovers must be properly patterned to ensure accurate disjunction of homologous chromosomes during meiosis I. Disruption of the spatial distribution of crossovers can lead to nondisjunction, aneuploidy, gamete dysfunction, miscarriage, or birth defects. One of the earliest identified genes involved in proper crossover patterning is Drosophila mei-41, which encodes the ortholog of the checkpoint kinase...

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Identifiers

PMID: 29247012
DOI: 10.1534/genetics.117.300634
PMCID: PMC5788523

Genes

ATR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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