Article
ATR signaling at a glance
21 Jan 2009
Abstract excerpt
The maintenance of genomic integrity is crucial for the survival of all organisms. In humans, compromised genomic integrity contributes to genetic disorders, aging and cancers. The task of safeguarding the genome is accomplished by the concerted action of a number of cellular processes, including DNA replication, DNA repair, senescence and apoptosis. Many, if not all, of these processes are regulated and...
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