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Article

Free energy of DNA duplex formation on short oligonucleotide microarrays.

Nucleic acids research - 1 Jan 2007

Zhang Li, Wu Chunlei, Carta Roberto, Zhao Haitao

Abstract excerpt

DNA/DNA duplex formation is the basic mechanism that is used in genome tiling arrays and SNP arrays manufactured by Affymetrix. However, detailed knowledge of the physical process is still lacking. In this study, we show a free energy analysis of DNA/DNA duplex formation these arrays based on the positional-dependent nearest-neighbor (PDNN) model, which was developed previously for describing DNA/RNA duplex...

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Identifiers

PMID: 17169993
DOI: 10.1093/nar/gkl1064
PMCID: PMC1807971

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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