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Article

Analysis of the factors affecting the accuracy of detection for single base alterations by oligonucleotide microarray.

Experimental & molecular medicine - 30 Apr 2005

Liu Sanzhen, Li Yao, Fu Xuping, Qiu Minyan, Jiang Bin, Wu Hai, Li Rongyu, Mao Yumin, Xie Yi

Abstract excerpt

The oligonucleotide microarray, a high-throughput polymorphism detection technology, holds great promise for the characterization of complex genetic variance. To achieve greater sensitivity and specificity for it to be an effective platform technology we present results and discuss some of the factors influencing signal intensities and single-mismatch discrimination in array-based mutation/SNP detection. Probes...

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PMID: 15886519
DOI: 10.1038/emm.2005.10

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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