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Article

Development of a physical model-based algorithm for the detection of single-nucleotide substitutions by using tiling microarrays.

PloS one - 1 Jan 2013

Ono Naoaki, Suzuki Shingo, Furusawa Chikara, Shimizu Hiroshi, Yomo Tetsuya

Abstract excerpt

High-density DNA microarrays are useful tools for analyzing sequence changes in DNA samples. Although microarray analysis provides informative signals from a large number of probes, the analysis and interpretation of these signals have certain inherent limitations, namely, complex dependency of signals on the probe sequences and the existence of false signals arising from non-specific binding between probe and...

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Identifiers

PMID: 23382915
DOI: 10.1371/journal.pone.0054571
PMCID: PMC3557292

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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